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International Society for Extracellular Vesicles workshop. QuantitatEVs: Multiscale analyses, from bulk to single extracellular vesicle
Summary
This workshop report summarizes discussions among scientists about improving methods for measuring and analyzing extracellular vesicles, which are tiny particles released by cells. Researchers explored strategies for standardizing both laboratory techniques and computational approaches, from bulk samples down to individual vesicles. The report identifies key challenges and emerging technologies needed to advance this rapidly growing field of biomedical research.
The 'QuantitatEVs: multiscale analyses, from bulk to single vesicle' workshop aimed to discuss quantitative strategies and harmonized wet and computational approaches toward the comprehensive analysis of extracellular vesicles (EVs) from bulk to single vesicle analyses with a special focus on emerging technologies. The workshop covered the key issues in the quantitative analysis of different EV-associated molecular components and EV biophysical features, which are considered the core of EV-associated biomarker discovery and validation for their clinical translation. The in-person-only workshop was held in Trento, Italy, from January 31<sup>st</sup> to February 2<sup>nd</sup>, 2023, and continued in Milan on February 3<sup>rd</sup> with "Next Generation EVs", a satellite event dedicated to early career researchers (ECR). This report summarizes the main topics and outcomes of the workshop.
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