0
Article Tier 2 Nanoplastics Sign in to save

Unraveling the micro- and nanoplastic predicament: A human-centric insight

The Science of The Total Environment 2024 17 citations

AI summary Read the abstract

This review summarizes what is currently known about micro- and nanoplastic exposure in humans, covering how particles circulate in the environment and accumulate in over 15 different human organs and tissues. The authors analyzed data from 91 toxicity studies and evaluated whether the plastic types and sizes used in experiments reflect real-world human exposure. The review highlights that while evidence of human plastic accumulation is growing, more research with environmentally realistic conditions is needed to truly understand health risks.

Micro- and nanoplastics are vast anthropogenic pollutants in our direct surroundings with a robust environmental stability and a potential for a long-lasting and increasing global circulation. This has raised concerns among the public and policy makers for human health upon exposure to these particles. The micro- and nanoplastic burden on humans is currently under debate, along with criticism on the experimental approaches used in hazard assessment. The present review presents an overview of the human-relevant aspects associated with the current micro-and nanoplastic burden. We focus on environmental circulation and the estimation of exposure quantities to humans, along with a state-of-the-art overview of particle accumulation in over 15 human organs and other specimen. Additionally, data regarding particle characteristics used in toxicity testing was extracted from 91 studies and discussed considering their environmental and human relevance.

More Papers Like This

Article Tier 2

Micro and nano-plastics, a threat to human health?

AI summary Read the abstract

This review examines the threat micro- and nanoplastics pose to human health, discussing how these persistent particles accumulate in organs including lungs, the gastrointestinal system, and blood, and how their chemical composition and size influence toxicity.

Article Tier 2

Systemic translocation of micro- and nanoplastics in humans: Evidence, mechanisms and future perspectives

AI summary Read the abstract

This review summarizes existing research on tiny plastic particles found in human tissues like the placenta, lungs, liver, kidneys, and brain. It examines how these particles might move through the body, based mainly on lab and animal studies, and notes that detection methods and human evidence still have major limitations.

Article Tier 2

"Micro and Nano Plastic as an Emerging Threat on Human Health"

AI summary Read the abstract

This review covers the sources, environmental prevalence, and human health effects of micro- and nanoplastics, summarizing how these particles—derived from tire wear, synthetic fibers, and product breakdown—accumulate in and affect major organs including the brain, liver, kidneys, and reproductive system. It identifies gaps in clinical evidence and calls for coordinated research on long-term health impacts.

Article Tier 2

A critical review of micro- and nanoplastic permeation in the human body

AI summary Read the abstract

This critical review examines how micro- and nanoplastics enter and move through the human body after exposure through food, beverages, and air. Researchers synthesized evidence showing these particles have been detected in multiple human tissues and organs, raising concerns about their potential long-term health effects from chronic environmental exposure.

Systematic Review Tier 1

Unveiling the presence of micro and nanoplastics in human biological matrices: A systematic review covering the latest five years from 2020 to 2025

AI summary Read the abstract

This systematic review covering 2020-2025 confirmed the presence of micro- and nanoplastics in human blood, placenta, lungs, liver, kidneys, and other biological matrices. The findings demonstrate that plastic particles are accumulating in human tissues through ingestion, inhalation, and dermal contact, raising urgent questions about long-term health consequences.

Research digests by email

When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.

Email me about

Share this paper