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Editorial: Mammalian spermatogenesis: genetic and environmental factors
Summary
This editorial introduces a research collection on mammalian spermatogenesis, examining both genetic and non-genetic environmental factors that can disrupt the tightly regulated process from spermatogonial proliferation through spermatozoa maturation and lead to male infertility.
Mammalian Spermatogenesis: Genetic and Environmental Factors 10 Spermatogenesis is a complex and tightly regulated process, which includes the proliferation of 11 spermatogonia, spermatogonia differentiation into spermatocytes, meiotic division of spermatocytes 12 producing spermatids, maturation of round spermatids and the release of highly specialized mature 13 spermatozoa (Neto et al., 2016). Abnormalities in any of these events could lead to spermatogenesis 14 disorders that affect fertility. Spermatogenesis disorders can be caused by genetic and non-genetic 15 factors, of which genetic accounts for 15-30% and non-genetic accounts for 70-85%
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