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Clinical and diagnostic values of metagenomic next-generation sequencing for infection in hematology patients: a systematic review and meta-analysis

BMC Infectious Diseases 2024 15 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 70 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Yu‐Hui Chen, Yu‐Hui Chen, Jinjin Wang, Ting Niu Ting Niu Ting Niu

Summary

Researchers conducted a systematic review and meta-analysis showing that metagenomic next-generation sequencing (mNGS) — a technology that identifies pathogens by reading their DNA — achieves high detection rates for infections in blood cancer patients. The findings suggest mNGS can guide antibiotic decisions and improve patient outcomes, particularly in China where the evidence base is strongest.

mNGS has high positive detection rates in hematology patients. mNGS can guide clinical antibiotic adjustments and improve prognosis, especially in China.

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