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Plasmonic Dielectric Antennas for Hybrid Optical Nanotweezing And Optothermoelectric Manipulation of Single Nanosized Extracellular Vesicles
Summary
Researchers experimentally demonstrated near-field optical trapping and dynamic manipulation of individual extracellular vesicles using a plasmonic dielectric nanoantenna designed to support an optical anapole state. The technique offers a new tool for studying and manipulating nanoscale biological particles without mechanical contact.
This paper showcases an experimental demonstration of near-field optical trapping and dynamic manipulation of an individual extracellular vesicle. This is accomplished through the utilization of a plasmonic dielectric nanoantenna designed to support an optical anapole state-a non-radiating optical state resulting from the destructive interference between electric and toroidal dipoles in the far-field, leading to robust near-field enhancement. To further enhance the field intensity associated with the optical anapole state, a plasmonic mirror is incorporated, thereby boosting trapping capabilities. In addition to demonstrating near-field optical trapping, the study achieves dynamic manipulation of extracellular vesicles by harnessing the thermoelectric effect. This effect is induced in the presence of an ionic surfactant, cetyltrimethylammonium chloride (CTAC), combined with plasmonic heating. Furthermore, the thermoelectric effect improves trapping stability by introducing a wide and deep trapping potential. In summary, our hybrid plasmonic-dielectric trapping platform offers a versatile approach for actively transporting, stably trapping, and dynamically manipulating individual extracellular vesicles.
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