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In vitro degradation behavior of oriented microcellular poly(L-lactic acid) biomimetic materials
Summary
This study characterized the in vitro hydrolytic degradation behavior of oriented microcellular poly(L-lactic acid) biomimetic materials, finding that molecular chain orientation and cellular microstructure influence the rate and pattern of degradation.
This paper investigated the static in vitro degradation behavior of poly(L-lactic acid) (PLLA)-oriented microcellular materials. The study compared the influence of different molecular chains and internal morphological structures on water penetration into the material. Also, the relationship between thse self-accelerated degradation caused by ester bond breakage and reduced material molecular weight and mechanical properties was explored. Furthermore, the mechanism behind the static in vitro degradation of oriented microcellular PLLA materials in simulated human body fluid was explored, laying the foundation for regulating the mechanical performance decline of oriented microcellular biomimetic bone repair materials to match specific bone healing periods.
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