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An Ex Vivo Study Examining Migration of Microplastics from an Infused Neonatal Parenteral Nutrition Circuit

Environmental Health Perspectives 2024 5 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Maaike Vercauteren, Lucas Panneel, Philippe G. Jorens, Adrian Covaci, Paulien Cleys, Antonius Mulder, Colin Janssen, Jana Asselman

Summary

This ex vivo study quantified microplastics released from neonatal parenteral nutrition infusion circuits, finding that plastic particles migrate from the tubing and connectors into infused solutions, raising concerns about iatrogenic microplastic exposure in vulnerable neonatal patients.

Figure 1. Overview of microplastic concentration (A), polymer composition (B), and size distribution (C) in the crystalloid solution collected in a simulated parenteral nutrition circuit and administered over a course of maximum 72 h with samples at time 0 (T0), T12, T24, T48, T72. The T0 measurements represent information on microplastics in the original fluid, without transition through the circuits. The number of samples per time point is indicated in panel A with "N=." Two particles (size 976 and 1,274:9 lm) are not included in the figure of the size distribution (Figure Plastic polymer types (Figure Corresponding numeric data of the figure can be found in Supplementary data at https://zenodo.org/records/10102884 ("Supporting data -Numeric data.docx").

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