We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Quantitative monitoring of microplastics and lipid metabolism in live zebrafish via hyperspectral stimulated Raman scattering microscopy
AI summary Read the abstract
Researchers used spectral focusing hyperspectral stimulated Raman scattering (SRS) microscopy to longitudinally monitor microplastic uptake, size-dependent organ accumulation, and lipid metabolic changes in live zebrafish during development. They found that microplastic exposure disrupted hepatic lipid metabolism and energy homeostasis, with the SRS imaging approach enabling real-time, label-free tracking of microplastics and associated biochemical changes in living organisms.
We utilize spectral focusing hyperspectral stimulated Raman scattering (SRS) imaging for longitudinally assessment of the interactions between live zebrafish and microplastics (MP) throughout the development process. Our study delves into the pathways of MP uptake and the size-dependent accumulation of MP within different zebrafish organs during various developmental phases. The altered lipid metabolic dynamics uncovered by Raman-tagged hyperspectral SRS imaging further reveal the hepatic inflammation and disruptions in energy metabolism within MP-exposed zebrafish, providing fresh insights on the potential impacts and fate of MP on diverse living organisms.
More Papers Like This
Quantitative assessment and monitoring of microplastics and nanoplastics distributions and lipid metabolism in live zebrafish using hyperspectral stimulated Raman scattering microscopy
AI summary Read the abstract
Researchers developed a new imaging technique to watch microplastics and nanoplastics accumulate in live zebrafish in real time, without needing dyes or labels. They found that these tiny plastic particles built up in the fish's digestive system and disrupted fat metabolism, providing direct visual evidence of how micro- and nanoplastics can interfere with basic biological processes.
Label-free stimulated Raman scattering imaging of intracellular microplastics in mammalian cells
AI summary Read the abstract
Researchers used label-free stimulated Raman scattering imaging to visualize microplastic uptake and distribution inside mammalian cells without fluorescent labels, finding that intracellular microplastics were associated with elevated reactive oxygen species, reduced cell viability, and altered lipid metabolism.
Hyperspectral oblique plane microscopy enables spontaneous, label-free imaging of biological dynamic processes in live animals
AI summary Read the abstract
Researchers developed a new high-speed Raman imaging microscope that can capture label-free, molecular-level images of biological processes in living animals. They demonstrated the technology by tracking microplastic accumulation in the organs of live zebrafish, visualizing particle distribution without any dyes or markers. This imaging advancement could significantly improve how scientists study microplastic uptake and distribution in living organisms.
Visible Combined Near-Infrared in Situ Imaging Revealed Dynamic Effects of Microplastic Fibers and Beads in Zebrafish
AI summary Read the abstract
Researchers used a combined visible and near-infrared imaging technique to track microplastic fibers and beads in live zebrafish in real time. They observed that microplastics were quickly ingested and could be retained briefly in the digestive tract before being eliminated. The study provides new insights into the dynamic behavior of microplastics inside living organisms and whether any tissue damage that occurs during transit can be reversed.
Label-free 4D confocal Raman imaging enabling in vivo multiplex identification of microplastics in zebrafish
AI summary Read the abstract
Scientists created a new imaging technique that can track five different types of microplastics inside living zebrafish at the same time, without needing to add dyes or chemical tags that could alter the results. They found that different plastic types build up in the gut at different rates, with noticeable accumulation after just 8 hours of exposure, a tool like this could help researchers better understand how the mix of plastics we're exposed to in real life actually moves through and affects living bodies, which matters since humans regularly ingest microplastics from food and water.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.