We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Effects of two typical quinolone antibiotics in the marine environment on Skeletonema costatum
Summary
This study tested the effects of two common antibiotic drugs, levofloxacin and norfloxacin, on the marine algae Skeletonema costatum. Researchers found that both antibiotics inhibited algal growth, reduced chlorophyll content, and triggered oxidative stress responses, indicating that pharmaceutical pollution in marine environments can disrupt the base of the ocean food web.
This study investigated the effects of levofloxacin (LEV) and norfloxacin (NOR) on Skeletonema costatum , focusing on cell growth, chlorophyll a (Chla) content, maximal quantum yield of PSII ( Fv/Fm ), protein content, enzyme activities of superoxide dismutase (SOD), glutathione reductase (GR), and glutathione peroxidase (GSH-PX), and the membrane lipid peroxidation product malondialdehyde (MDA) content were conducted to analyze the responses of S. costatum under LEV and NOR exposure. Cell growth, Chla content, Fv/Fm , protein content, enzyme activities, and MDA content were assessed to elucidate physiological changes. Both LEV and NOR inhibited S. costatum growth, except for 10 mg/L NOR, which promoted growth. Algal cells exhibited higher sensitivity to LEV, with 96h-IC50 values of 14.770 mg/L for LEV and 44.250 mg/L for NOR. Low NOR concentration (10 mg/L) increased Chla content, while high antibiotic concentrations (>20 mg/L for LEV, >100 mg/L for NOR) decreased Chla content and Fv/Fm , indicating an impact on photosynthesis. Elevated LEV and NOR levels reduced protein and MDA content but increased GR, SOD, and GSH activities, indicating induced oxidative stress. The study provides a comprehensive analysis of LEV and NOR effects on marine microalgae growth and underlying physiological mechanisms, shedding light on potential ecological risks posed by antibiotics in marine ecosystems.
Sign in to start a discussion.
More Papers Like This
Microplastics decrease the toxicity of sulfamethoxazole to marine algae (Skeletonema costatum) at the cellular and molecular levels
Researchers investigated the combined toxicity of the antibiotic sulfamethoxazole and five types of microplastics on the marine alga Skeletonema costatum. They found that certain microplastics actually decreased the toxicity of the antibiotic by adsorbing it, creating a protective "shelter" effect, though polystyrene combined with the antibiotic caused higher oxidative stress. The study suggests that microplastics can alter the bioavailability and toxicity of co-occurring pollutants in marine environments through adsorption interactions.
The Toxic Effects of Antibiotics on Freshwater and Marine Photosynthetic Microorganisms: State of the Art
This review summarizes the toxic effects of over 60 antibiotics on freshwater and marine photosynthetic microorganisms. Researchers found that 60% of the available toxicity data comes from a single freshwater algae species, with marine species vastly understudied. The study highlights critical knowledge gaps in chronic antibiotic exposure effects and calls for research using environmentally relevant concentrations and combined exposure scenarios.
Joint toxicity of microplastics with triclosan to marine microalgae Skeletonema costatum
Researchers investigated the combined toxicity of triclosan and four types of microplastics on the marine microalga Skeletonema costatum. They found that while all microplastics individually inhibited algal growth, PVC and smaller particles had the strongest effects, and the joint toxicity with triclosan followed an antagonistic pattern rather than additive or synergistic. The study suggests that microplastics can adsorb organic pollutants and partially reduce their bioavailability, though the physical damage from smaller particles remains a significant concern.
Response of Marine Microalgae Tetraselmis chuii to 5 Groups of Antibiotics
Researchers tested three doses of five antibiotic groups (quinolones, tetracyclines, penicillins, macrolides, and sulfonamides) on the marine green microalgae Tetraselmis chuii, measuring cell density, dry biomass, specific growth rate, and chlorophyll content as stress biomarkers. Tetracyclines, penicillins, and sulfonamides inhibited algal growth at all tested doses, while effects among quinolones varied by specific compound.
Behavior of tetracycline and polystyrene nanoparticles in estuaries and their joint toxicity on marine microalgae Skeletonema costatum
Researchers studied the sorption of tetracycline antibiotic onto polystyrene nanoparticles in simulated estuarine conditions and found that the combination was more toxic to the marine diatom Skeletonema costatum than either stressor alone, due to enhanced cellular uptake of antibiotic delivered by nanoplastics.