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Functional roles of circular RNAs in lung injury

Frontiers in Pharmacology 2024 3 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 50 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.

Feifei Gao, Dian-Qing Chen, Dian-Qing Chen, Yuetong Jiang, Yuetong Jiang, Cui-Fei Han, Cui-Fei Han, Biyun Lin, Biyun Lin, Yang Zhan, Juan‐Hua Quan, Ying-Huan Xiong, Ying-Huan Xiong, Xintian Chen, Xintian Chen

Summary

This review examines the functional roles of circular RNAs in various forms of lung injury, including their involvement in disease progression. The study suggests that understanding circRNA mechanisms could lead to new insights into respiratory damage pathways, though the connection to environmental exposures requires further investigation.

Body Systems

Respiratory

Lung injury leads to respiratory dysfunction, low quality of life, and even life-threatening conditions. Circular RNAs (circRNAs) are endogenous RNAs produced by selective RNA splicing. Studies have reported their involvement in the progression of lung injury. Understanding the roles of circRNAs in lung injury may aid in elucidating the underlying mechanisms and provide new therapeutic targets. Thus, in this review, we aimed to summarize and discuss the characteristics and biological functions of circRNAs, and their roles in lung injury from existing research, to provide a theoretical basis for the use of circRNAs as a diagnostic and therapeutic target for lung injury.

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