We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Long-term exposure of endangered Danube sturgeon (Acipenser gueldenstaedtii) to bisphenol A (BPA): growth, behavioral, histological, genotoxic, and hematological evaluation
AI summary Read the abstract
Researchers exposed endangered Danube sturgeon to bisphenol A (BPA), a chemical used in plastics, finding that even low concentrations reduced growth, damaged liver tissue, caused DNA strand breaks, and disrupted blood cell counts — raising concern for wild fish populations living in BPA-contaminated waterways.
Danube sturgeon (Acipenser gueldenstaedtii) which is identified as endangered species can be exposed to pollutants such as bisphenol A (BPA) that have a disruptive effect on the endocrine system at any time. Starting from this motivation, the current study focused on BPA toxicity in A. gueldenstaedtii juvenile individuals and its adverse effects in sub-lethal concentration. The median lethal concentration (LC50) of BPA was 5.03 mg/L in 96th hour. In the chronic period, 0.625 mg/L and 1.25 mg/L BPA concentrations were evaluated based on the result of acute study. Accordingly, growth performance was significantly decreased in BPA groups (1.25 mg/L BPA group was significantly lowest) compared to control (p < 0.05). In the acute period, behavioral disorders were standing at the bottom/corner of tank, slowing and stopping of gill movement, decreased response to stimuli, and death, respectively. While vacuolization was severe in the liver tissue of the fish in the acute period, intense necrosis and melanomacrophage centers were observed in the chronic period. In terms of genotoxicity, longer DNA migration was observed in all groups exposed to BPA than in the control group. In addition, lower erythrocyte and hemoglobin were observed in the BPA groups compared to control. As a result, the current study revealed toxic effect of BPA on A. gueldenstaedtii juvenile individuals and its negative results on fish physiology.
More Papers Like This
Bisphenol A Induces Histopathological, Hematobiochemical Alterations, Oxidative Stress, and Genotoxicity in Common Carp (Cyprinus carpio L.)
AI summary Read the abstract
Researchers investigated the toxic effects of bisphenol A, a plastics-related endocrine disruptor, on common carp at different dose levels over 30 days. The study found dose-dependent reductions in blood cell counts, increased oxidative stress in the brain, liver, gills, and kidneys, and significant tissue damage, indicating that BPA exposure poses risks to aquatic organisms.
Bisphenol A Used in Plastic Industry Negatively Affects Wild Vimba Bream (Vimba vimba)
AI summary Read the abstract
Researchers found that long-term exposure of wild vimba bream to bisphenol A caused significant histopathological damage in liver and gill tissues and altered antioxidant enzyme activity, demonstrating the endocrine-disrupting chemical's harmful effects on freshwater fish.
New Insights Into Hematological, Serum Biochemical and Histopathological Toxicity of Bisphenol a on Bighead Carp (Aristichthys Nobils) Under Long-Term Exposure
AI summary Read the abstract
Bighead carp exposed to bisphenol A (BPA) — a chemical used in plastic manufacturing — for 60 days showed organ damage, blood abnormalities, and hormonal disruption at higher doses. BPA leaches from plastics and represents a key chemical exposure pathway alongside microplastic ingestion.
Multi-mechanistic effects of bisphenol A on testicular dysfunction and endocrine disruption in adult male Labeo bata: oxidative stress, inflammation, and dysregulated energy sensors
AI summary Read the abstract
Researchers studied how bisphenol A (BPA), a chemical that leaches from microplastics in water, affects reproductive function in male fish. They found that chronic BPA exposure at environmentally relevant concentrations caused significant testicular damage, including reduced sperm production, increased inflammation, and disrupted hormone signaling. The study reveals multiple mechanisms by which this common microplastic-associated chemical can impair male reproductive health in aquatic species.
Sub‐Chronic Bisphenol‐A Toxicity in Climbing Perch, Anabas testudineus : Insight Into Metabolic Disruption, Oxidative Stress, and Histopathological Changes
AI summary Read the abstract
Researchers exposed climbing perch (Anabas testudineus) to sub-chronic doses of bisphenol-A, a plasticizer commonly released from degrading microplastics. The study found that BPA exposure caused significant metabolic disruption, oxidative stress, and histopathological damage in the fish, highlighting the indirect health risks that microplastic-derived chemicals pose to aquatic organisms.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.