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Human Ingestion of Micro-/Nanoplastics: A Simplified In Vitro Digestion Protocol for Cytotoxicity and Risk Assessment
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Researchers developed a simplified in vitro digestion protocol to better simulate how micro- and nanoplastics are biotransformed during human digestion, enabling more realistic cytotoxicity testing and risk assessment of plastic ingestion compared to prior models.
A comprehensive risk assessment of plastics’ health impacts is imperative; however, significant gaps exist in toxicity models that closely simulate human ingestion. The biotransformation of micro−/nanoplastics (MNPLs) during the digestion process, along...
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Toxicological Effects of Ingested Microplastics on Human Health
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Researchers reviewed the toxicological effects of ingested microplastics on human health, examining how these ubiquitous particles accumulate in the gastrointestinal tract and may cause inflammation, oxidative stress, and potential systemic harm across multiple organ systems.
Human Exposure to Dietary Microplastics and Health Risk: A Comprehensive Review
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This comprehensive review examines human dietary exposure to microplastics through bottled water, seafood, packaged foods, and crops grown in plastic-mulched soils, cataloging toxicity mechanisms including immune disruption, gastrointestinal damage, and developmental cytotoxicity, with MPs shown to transfer via placenta and breast milk. The multi-pathway exposure evidence reviewed here highlights that microplastic ingestion is a universal human experience beginning before birth, with plausible health consequences that demand urgent investment in mechanistic in vivo research.
Cellular and Animal Toxicities of Micro- and Nanoplastics
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Researchers reviewed evidence from cell and animal studies on the toxic effects of micro- and nanoplastics, finding that these particles can cause inflammation, oxidative stress, and organ damage in laboratory models, raising concern about what chronic low-level human exposure might mean for long-term health.
Human exposure to micro- and nanoplastics: routes, accumulation, and health implications
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This review synthesizes evidence that microplastics and nanoplastics have been detected in human blood, placenta, breast milk, and stool, with emerging associations between internal MNP burdens and inflammatory, cardiometabolic, and potential reproductive effects. Humans are exposed through ingestion, inhalation, skin contact, and medical interventions, making microplastic accumulation in the body a pressing public health concern requiring urgent research into clinical health outcomes.
Microplastics and nanoplastics in human health: a comprehensive review of exposure pathways, cellular mechanisms, and toxicological implications
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Researchers reviewed human exposure pathways to microplastics and nanoplastics through seafood, salt, drinking water, inhalation, and skin contact, examining how these particles cross biological barriers to reach organs and trigger oxidative stress, inflammation, and endocrine disruption with poorly understood long-term consequences.
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When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.