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Corrigendum to “Microplastics and PFAS as ubiquitous pollutants affect potencies of highly toxic chemicals in mixtures” [J Hazard Mater 500 (2025) 140493]

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Microplastics and PFAS as ubiquitous pollutants affect potencies of highly toxic chemicals in mixtures

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Researchers investigated how ubiquitous pollutants like PFAS and microplastics affect the toxicity of other highly toxic chemicals when present together in mixtures. They found that even at non-toxic concentrations, PFAS and microplastics could alter the potency of co-occurring toxic compounds. The study highlights the importance of considering pollutant interactions in complex environmental mixtures rather than assessing chemicals in isolation.

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Researchers reviewed the combined toxicity of PFAS and microplastics in aquatic ecosystems, finding that while synergistic interactions receive the most attention, additive and antagonistic outcomes are also common and depend on PFAS congener, polymer type, particle size, and species—warning against treating synergy as the default response and calling for standardized mixture-based exposure protocols to enable ecologically realistic risk assessment.

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