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Integrative Approaches to Aquatic Toxicology Using Bioinformatics
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This work applies bioinformatics and integrative computational approaches to aquatic toxicology, enabling researchers to model how pollutants including microplastics affect gene expression, metabolic pathways, and ecosystem-level responses in aquatic organisms. Integrating molecular and ecological data accelerates identification of the biological mechanisms by which microplastics harm aquatic life, strengthening the scientific basis for regulatory standards that protect both ecosystems and human health.
Aquatic ecosystems are crucial for maintaining ecological balance, yet they are increasingly threatened by pollutants such as pharmaceuticals, heavy metals, microplastics, and industrial chemicals. Aquatic toxicology plays a vital role in assessing and mitigating...
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Researchers review how rising global temperatures amplify the toxicity of emerging contaminants — including nanoplastics, heavy metals, and polycyclic aromatic hydrocarbons — in aquatic organisms, finding that warming increases oxidative stress, DNA damage, bioaccumulation, and biomagnification, threatening biodiversity in ways current risk assessments fail to capture.
Multi-omic Approach on the Ecotoxicological Assessment of Microplastics, Antibiotics and Their Co-exposure to Zebrafish
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This PhD thesis investigated co-exposure effects of microplastics and antibiotics on zebrafish using multi-omic approaches, examining transcriptomic, proteomic, and metabolomic responses. Combined exposure produced more complex molecular disruption than either stressor alone, with interactions affecting gut microbiome composition and host metabolic phenotype.
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Researchers reviewed the behavior of several emerging pollutants — including microplastics, phthalates, and antibiotics — in aquatic environments, highlighting how these contaminants spread through water systems and interact with ecosystems in ways that are still not fully understood.
Genotoxicity Biomarkers for Environmental Health Assessment Towards Sustainable Management of Fish Genetic Resources
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Researchers evaluated genotoxicity biomarkers in fish as tools for assessing environmental health in water bodies contaminated by chemicals, microplastics, heavy metals, and agricultural runoff. The paper proposes integrating these biomarkers into sustainable monitoring frameworks for protecting aquatic genetic resources from industrial and urban pollution.
Microplastic Contamination in Aquatic Organisms: An Ecotoxicological Perspective
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"This ecotoxicological review examined how microplastics accumulate in aquatic organisms across multiple trophic levels, documenting impacts on physiology, reproduction, and behavior, as well as the transport of associated chemical contaminants through food webs. Because humans sit at the top of aquatic food chains, the bioaccumulation dynamics described here translate directly into dietary microplastic exposure, making ecotoxicological endpoints in fish and shellfish key indicators of human health risk."
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