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Moms Matter: the Impact of Micro-/Nanoplastics on the Utero-Placental Circulation in Mice
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An exploration into the transplacental transfer of microplastics through placental transporters
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Researchers used molecular dynamics simulations to model how polystyrene and polyethylene nanoplastics interact with six key placental transport proteins, finding that PE nanoplastics have higher transplacental transfer potential than PS because fewer efflux transporters act to block their passage.
Health Risks of Prenatal and Early-Life Microplastics Exposure: A Comprehensive Review
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Researchers reviewed current evidence that microplastics cross the placental barrier and affect fetal development through oxidative stress, inflammation, endocrine disruption, and epigenetic alterations, summarizing experimental findings linking prenatal and early-life exposure to neurodevelopmental, reproductive, and immune abnormalities — often in a sex-dependent manner — while identifying major gaps in human dose-response data.
Microplastics, pregnancy and the placenta: what we know and what we don’t
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Researchers reviewed current evidence on microplastic accumulation in the placenta during pregnancy, examining what is known about how these particles cross or are blocked by placental tissue and what gaps remain regarding potential developmental consequences for the fetus.
Embryonic Exposure Towards Microplastic: Its Causes and Effects
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Researchers reviewed how embryonic and early-life exposure to microplastics and nanoplastics disrupts reproductive development and aquatic organism physiology, highlighting particular concern for developmental toxicity given the vulnerability of embryos to oxidative stress and endocrine disruption caused by plastic particles.
Unveiling micro-nanoplastics (MNPs) induced developmental toxicity, transgenerational transport and associated signaling pathways
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Tiny plastic particles from our environment can pass from a mother to her baby through the placenta and breast milk, and this review of existing animal research shows these particles can build up in offspring and potentially disrupt healthy development, causing issues like inflammation, cell damage, and hormone problems. While most of this evidence comes from animal studies so far, it's a wake-up call that plastic pollution may affect not just the people exposed to it, but their children too, making it worth pushing for both more research in humans and stronger policies to cut down plastic exposure.
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