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Systematic Review ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 1 ? Systematic review or meta-analysis. Synthesizes findings across many studies. Strongest evidence. Human Health Effects Policy & Risk Sign in to save

Dental microplastics as emerging neurotoxicants: a systematic review on human data

PeerJ 2026 Score: 60 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Aiah Alkhamees, Aiah Alkhamees, Dana Salha, Dana Salha, Dana Alfailat, Dana Alfailat, Danah Malallah, Danah Malallah, Dhewy Alazemi, Dhewy Alazemi, Dunia Al Taharweh, Dunia Al Taharweh, Ebaa Al Borom, Ebaa Al Borom, Asmaa Uthman, Asmaa Uthman, Musab Hamed Saeed, Natheer H. Al-Rawi, Natheer H. Al-Rawi

Summary

This research review looked at studies examining whether tiny plastic particles from dental sources might harm the brain and nervous system. The evidence suggests there could be a connection between microplastic exposure and neurological problems, but the studies done so far aren't strong enough to prove microplastics actually cause brain damage. More long-term research on real people is needed to determine if these microscopic plastics pose a genuine health risk to our nervous systems.

Body Systems
Models
Study Type Review

Current evidence indicates possible neurological effects of microplastics-related exposures, corroborated by similar molecular pathways in <i>in-vitro</i> research and connections identified in human cross-sectional data. Nevertheless, the primarily observational and experimental characteristics of existing studies hinder definitive conclusions about clinical causation. Additional longitudinal, standardized human investigations are required to elucidate dose-response relationships and the applicability of <i>in-vitro</i> findings to real-world exposure.

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