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Dental microplastics as emerging neurotoxicants: a systematic review on human data

PeerJ 2026

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This research review looked at studies examining whether tiny plastic particles from dental sources might harm the brain and nervous system. The evidence suggests there could be a connection between microplastic exposure and neurological problems, but the studies done so far aren't strong enough to prove microplastics actually cause brain damage. More long-term research on real people is needed to determine if these microscopic plastics pose a genuine health risk to our nervous systems.

Body Systems
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Study Type Review

Current evidence indicates possible neurological effects of microplastics-related exposures, corroborated by similar molecular pathways in in-vitro research and connections identified in human cross-sectional data. Nevertheless, the primarily observational and experimental characteristics of existing studies hinder definitive conclusions about clinical causation. Additional longitudinal, standardized human investigations are required to elucidate dose-response relationships and the applicability of in-vitro findings to real-world exposure.

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