S04-02 Redox-mediated toxicity of micro- and nanoplastics in intestinal models

Cellular and Animal Toxicities of Micro- and Nanoplastics

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Researchers reviewed evidence from cell and animal studies on the toxic effects of micro- and nanoplastics, finding that these particles can cause inflammation, oxidative stress, and organ damage in laboratory models, raising concern about what chronic low-level human exposure might mean for long-term health.

Toxicity Effects of Micro- and Nanoplastics in Terrestrial Environment

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Researchers examined how micro- and nanoplastics, along with their chemical additives such as bisphenols and phthalates, cause toxicity in terrestrial environments, highlighting how these synthetic polymer fragments disrupt soil ecosystems and expose organisms to compounded chemical hazards.

Molecular mechanisms of microplastics toxicity

Microplastics and nanoplastics in human health: a comprehensive review of exposure pathways, cellular mechanisms, and toxicological implications

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Researchers reviewed human exposure pathways to microplastics and nanoplastics through seafood, salt, drinking water, inhalation, and skin contact, examining how these particles cross biological barriers to reach organs and trigger oxidative stress, inflammation, and endocrine disruption with poorly understood long-term consequences.

The Interaction of Toxic Chemicals with Micro/Nanoplastics

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This work examines how micro- and nanoplastics interact with toxic environmental chemicals — including heavy metals, pesticides, and persistent organic pollutants — acting as vectors that concentrate and transport these substances through food chains and into living organisms. The combined toxic burden of plastics plus co-contaminants poses a substantially greater health risk than either pollutant class alone, a key consideration for understanding real-world human exposure to plastic pollution.