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Human Health Effects
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Exposure to microplastics contaminated with pharmaceuticals and personal care products: Histological effects on Ucides cordatus
The Science of The Total Environment2024
1 citation
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Score: 45
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0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Caio Rodrigues Nobre,
Caio Rodrigues Nobre,
Caio Rodrigues Nobre,
Beatriz Barbosa Moreno,
Caio Rodrigues Nobre,
Caio Rodrigues Nobre,
Caio Rodrigues Nobre,
Letícia Fernanda da Silva,
Letícia Fernanda da Silva,
Caio Rodrigues Nobre,
Rodrigo Brasil Choueri,
Caio Rodrigues Nobre,
Beatriz Barbosa Moreno,
Beatriz Barbosa Moreno,
Beatriz Barbosa Moreno,
Beatriz Barbosa Moreno,
Rodrigo Brasil Choueri,
Caio Rodrigues Nobre,
Caio Rodrigues Nobre,
Rodrigo Brasil Choueri,
Camilo Dias Seabra Pereira
Beatriz Barbosa Moreno,
Beatriz Barbosa Moreno,
Beatriz Barbosa Moreno,
Caio Rodrigues Nobre,
Camilo Dias Seabra Pereira
Caio Rodrigues Nobre,
Caio Rodrigues Nobre,
Caio Rodrigues Nobre,
Camilo Dias Seabra Pereira
Camilo Dias Seabra Pereira
Paloma Kachel Gusso‐Choueri,
Alexandre Rodrigo Nascimento Gonçalves,
Letícia Fernanda da Silva,
Augusto César,
Augusto César,
Alexandre Rodrigo Nascimento Gonçalves,
Augusto César,
Augusto César,
Beatriz Barbosa Moreno,
Paloma Kachel Gusso‐Choueri,
Caio Rodrigues Nobre,
Nathalia Sales Soares do Nascimento,
José Hérelis Carnaúba,
Paloma Kachel Gusso‐Choueri,
Letícia Fernanda da Silva,
Beatriz Barbosa Moreno,
Camilo Dias Seabra Pereira
Rodrigo Brasil Choueri,
Rodrigo Brasil Choueri,
Nathalia Sales Soares do Nascimento,
José Hérelis Carnaúba,
Paloma Kachel Gusso‐Choueri,
Letícia Fernanda da Silva,
Gabriela Pustiglione Marinsek,
Rodrigo Brasil Choueri,
Beatriz Barbosa Moreno,
Augusto César,
Renata de Britto Mari,
Beatriz Barbosa Moreno,
Beatriz Barbosa Moreno,
Augusto César,
Renata de Britto Mari,
Camilo Dias Seabra Pereira
Fábio Ruiz Simões,
Paloma Kachel Gusso‐Choueri,
Fábio Ruiz Simões,
Fábio Ruiz Simões,
Paloma Kachel Gusso‐Choueri,
Rodrigo Brasil Choueri,
José Hérelis Carnaúba,
José Hérelis Carnaúba,
Rodrigo Brasil Choueri,
Camilo Dias Seabra Pereira
Caio Rodrigues Nobre,
Rodrigo Brasil Choueri,
Paloma Kachel Gusso‐Choueri,
Paloma Kachel Gusso‐Choueri,
Paloma Kachel Gusso‐Choueri,
Paloma Kachel Gusso‐Choueri,
Camilo Dias Seabra Pereira
Camilo Dias Seabra Pereira
Augusto César,
Augusto César,
Augusto César,
Augusto César,
Camilo Dias Seabra Pereira
Summary
Crabs (Ucides cordatus) exposed to microplastics contaminated with triclosan or 17α-ethinylestradiol showed histological gill changes more severe than those from virgin microplastics alone, demonstrating that pharmaceutical and personal care product contaminants adsorbed on MPs increase tissue-level toxicity.
Pharmaceuticals and personal care products (PPCPs) are known to interact with microplastics (MPs) in aquatic environments, with substances such as the antimicrobial triclosan (TCS) and the synthetic hormone 17α-ethinylestradiol (EE2) being prevalent. These persistent contaminants are linked to toxic effects in aquatic organisms. This study aimed to investigate histological and morphometric changes in the gills of Ucides cordatus exposed to microplastics alone and microplastics contaminated with PPCPs. The experimental design included four treatment groups: 1) control (C), 2) virgin microplastics (MP), 3) microplastics fortified with triclosan (MPT), and 4) microplastics fortified with 17α-ethinylestradiol (MPE), with exposure durations of 3 or 7 days. Significant differences were observed in the histopathological indices for treatments with PPCP-fortified microplastics at 3 days (MPT and MPE) and 7 days (MPT). Notable pathologies included necrosis, fibrosis, and circulatory disorders. Exposure duration was significantly associated with morphometric changes, including secondary lamellar width in MPT and secondary lamellar length in MPE. These findings indicate that exposure to microplastics contaminated with PPCPs may impair the osmoregulatory and respiratory functions of Ucides cordatus.