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Article ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 2 ? Original research — experimental, observational, or case-control study. Direct primary evidence. Human Health Effects Sign in to save

Nano-Selenium Modulates NF-κB/NLRP3 Pathway and Mitochondrial Dynamics to Attenuate Microplastic-Induced Liver Injury

Nutrients 2024 10 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Qi Shen, Jia Liu, Jiakui Li, Donghai Zhou

Summary

Researchers found that nano-selenium particles could reduce liver inflammation caused by polystyrene microplastics in mice by regulating mitochondrial dynamics and modulating the NF-kB/NLRP3 inflammatory pathway. The study suggests that selenium nanoparticles may help counteract the inflammatory damage that microplastics cause in liver tissue, offering a potential avenue for mitigating microplastic-related organ injury.

Body Systems
Hepatic Immune
Models
Mouse

To summarize, the use of SeNPs hindered inflammation by regulating mitochondrial dynamics, thus relieving liver damage caused by PS-MPs in mice. The anticipated outcomes offer new research directions that can be referenced in terms of inflammatory injuries caused by PS-MPs.

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