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Biological hazards of micro- and nanoplastic with adsorbents and additives
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This review summarizes a decade of research on the biological hazards of microplastics and nanoplastics, including how their size, type, and adsorbed chemicals affect living organisms. Researchers found that smaller nanoplastics pose heightened risks because they are more easily absorbed by cells and tissues through ingestion, inhalation, and skin contact. The study emphasizes the need for further research into the long-term health effects of accumulating plastic particles in the environment and in the body.
With the increased worldwide production of plastics, interest in the biological hazards of microplastics (MP) and nanoplastics (NP), which are widely distributed as environmental pollutants, has also increased. This review aims to provide a comprehensive overview of the toxicological effects of MP and NP on in vitro and in vivo systems based on studies conducted over the past decade. We summarize key findings on how the type, size, and adsorbed substances of plastics, including chemical additives, impact organisms. Also, we address various exposure routes, such as ingestion, inhalation, and skin contact, and their biological effects on both aquatic and terrestrial organisms, as well as human health. Additionally, the review highlights the increased toxicity of MP and NP due to their smaller size and higher bioavailability, as well as the interactions between these particles and chemical additives. This review emphasizes the need for further research into the complex biological interactions and risks posed by the accumulation of MP and NP in the environment, while also proposing potential directions for future studies.
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Unseen Hazards—Toxicological Effects and Human Health Impacts of Nanoplastics and Microplastics
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This review covers the toxicological effects of microplastics and nanoplastics in humans, examining exposure routes (oral, inhalation, dermal), tissue distribution, and mechanisms of harm including oxidative stress, inflammation, and endocrine disruption. It emphasises the importance of particle size, polymer type, and adsorbed chemical additives in determining toxicity.
Toxicological considerations of nano-sized plastics
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This review examined the toxicological considerations specific to nanoplastics, focusing on how particle deposition in different biological compartments, physical properties (size, shape, surface chemistry), and chemical additives interact to determine biological effects. The authors argue that understanding nanoplastic toxicology requires shifting focus from exposure characterization to mechanistic biological relevance at the tissue and organ level.
New insights in to the environmental behavior and ecological toxicity of microplastics
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This review provides new insights into how microplastics behave in the environment and their toxic effects on living organisms. Microplastics can absorb and carry other pollutants, making them more dangerous than the plastic alone, and their effects vary based on size, shape, and chemical composition. The review highlights that smaller particles, especially nanoplastics, pose the greatest risk because they can cross biological barriers and enter cells.
Human exposure to micro- and nanoplastic: biological effects and health consequence
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This review summarized the biological effects and health consequences of human exposure to micro- and nanoplastics, covering routes of uptake (ingestion, inhalation, dermal), cellular toxicity mechanisms, and systemic health risks identified in recent experimental and epidemiological studies.
Micro and nano-plastics, a threat to human health?
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This review examines the threat micro- and nanoplastics pose to human health, discussing how these persistent particles accumulate in organs including lungs, the gastrointestinal system, and blood, and how their chemical composition and size influence toxicity.
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