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Does Bisphenol A (BPA) Exposure Cause Human Diseases?
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This review examined whether bisphenol A exposure directly causes human diseases or whether elevated BPA levels are simply a marker of other unhealthy behaviors. The evidence reviewed supports the indirect marker hypothesis, suggesting that higher BPA levels may reflect lifestyle factors like processed food consumption rather than BPA itself causing disease. The findings highlight the importance of distinguishing correlation from causation in environmental health research.
A review of the existing literature supports the indirect 'marker' hypothesis over the 'direct' hypothesis.
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Critical Analysis of Human Exposure to Bisphenol A and Its Novel Implications on Renal, Cardiovascular and Hypertensive Diseases
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This critical review analyzed urinary BPA concentration data across major population studies and found widespread human exposure to bisphenol A, with mounting evidence linking chronic low-level BPA exposure to renal, cardiovascular, and hypertensive diseases through its endocrine-disrupting mechanisms.
Temporal and geographic variability of bisphenol levels in humans: A systematic review and meta-analysis of international biomonitoring data
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Researchers conducted a systematic review and meta-analysis of global biomonitoring data and found evidence of increasing population-wide exposure to bisphenol A (BPA) and the replacement chemical BPS, raising concerns about the chemicals' impact on public health and economies worldwide.
Investigating hsCRP as a clinical inflammation marker for human Bisphenol A food contamination offers protocol suggestions for conducting replicable, causal dietary intervention studies
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This paper proposes a novel human dietary study design to test whether bisphenol A (BPA) — a plastic-derived chemical — causes inflammation, using the blood marker hsCRP as an outcome measure. The authors argue that previous BPA studies failed to be replicable or causally definitive, and offer a stricter protocol to fill that gap.
Bisphenol A-an Overview on its Effect on Health and Environment
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This review synthesized evidence on bisphenol A (BPA) — a chemical used in polycarbonate plastics and epoxy resins — covering its sources of human exposure, endocrine-disrupting mechanisms, and associations with metabolic, reproductive, and developmental health outcomes.
Plastic and its Side Effects on Humans – A Review Article
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This review examines the widespread use of plastics in daily life and their harmful side effects on human health, including the release of toxic chemicals like BPA and phthalates that act as endocrine disruptors and contribute to various diseases.
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When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.