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Commentary ? AI-assigned paper type based on the abstract. Classification may not be perfect — flag errors using the feedback button. Tier 3 ? Commentary, letter, editorial, or conference abstract. Useful context, not primary evidence. Detection Methods Nanoplastics Sign in to save

Response on the commentary by B. Wilhelmus, M. Gahleitner, and M. A. Pemberton, on the manuscript by M. Brits, M.J.M. van Velzen, F.Ö. Sefiloglu, L. Scibetta, Q. Groenewoud, J.J. Garcia-Vallejo, A.D. Vethaak, S.H. Brandsma, M.H. Lamoree. Quantitation of micro and nanoplastics in human blood by pyrolysis-gas chromatography–mass spectrometry: a follow-up study. Microplastics and Nanoplastics (2024) 4:12

Microplastics and Nanoplastics 2024 1 citation ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 35 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Feride Öykü Sefiloğlu, Feride Öykü Sefiloğlu, Feride Öykü Sefiloğlu, Lorenzo Scibetta, Martin Brits, M.H. Lamoree Martin Brits, Lorenzo Scibetta, Martin Brits, Feride Öykü Sefiloğlu, M.H. Lamoree Feride Öykü Sefiloğlu, Feride Öykü Sefiloğlu, Lorenzo Scibetta, Lorenzo Scibetta, Martin Brits, Lorenzo Scibetta, Lorenzo Scibetta, Lorenzo Scibetta, Martin J. M. van Velzen, Martin J. M. van Velzen, Lorenzo Scibetta, Martin J. M. van Velzen, M.H. Lamoree Lorenzo Scibetta, Martin Brits, Martin J. M. van Velzen, Martin Brits, Sicco H. Brandsma, Lorenzo Scibetta, Martin Brits, Feride Öykü Sefiloğlu, Martin J. M. van Velzen, M.H. Lamoree Martin Brits, Martin Brits, Martin Brits, Martin Brits, Martin Brits, Martin Brits, Martin Brits, Martin Brits, Martin J. M. van Velzen, Lorenzo Scibetta, Feride Öykü Sefiloğlu, Feride Öykü Sefiloğlu, Martin J. M. van Velzen, Lorenzo Scibetta, M.H. Lamoree Lorenzo Scibetta, Lorenzo Scibetta, Lorenzo Scibetta, Martin J. M. van Velzen, Martin J. M. van Velzen, Lorenzo Scibetta, Lorenzo Scibetta, Martin J. M. van Velzen, Martin J. M. van Velzen, Martin J. M. van Velzen, Lorenzo Scibetta, Martin Brits, Martin J. M. van Velzen, Martin J. M. van Velzen, Martin J. M. van Velzen, Sicco H. Brandsma, M.H. Lamoree Lorenzo Scibetta, Quinn Groenewoud, Sicco H. Brandsma, Feride Öykü Sefiloğlu, Feride Öykü Sefiloğlu, Quinn Groenewoud, Quinn Groenewoud, Quinn Groenewoud, Quinn Groenewoud, Sicco H. Brandsma, Quinn Groenewoud, M.H. Lamoree Juan J. García‐Vallejo, Juan J. García‐Vallejo, M.H. Lamoree M.H. Lamoree M.H. Lamoree Quinn Groenewoud, Quinn Groenewoud, M.H. Lamoree M.H. Lamoree M.H. Lamoree Sicco H. Brandsma, Sicco H. Brandsma, M.H. Lamoree M.H. Lamoree M.H. Lamoree Sicco H. Brandsma, Sicco H. Brandsma, M.H. Lamoree M.H. Lamoree M.H. Lamoree Sicco H. Brandsma, M.H. Lamoree M.H. Lamoree M.H. Lamoree M.H. Lamoree Martin Brits, M.H. Lamoree Martin Brits, M.H. Lamoree M.H. Lamoree

Summary

Researchers responded to peer criticism of their study measuring microplastics and nanoplastics in human blood using pyrolysis gas chromatography-mass spectrometry, defending their methods for identifying and quantifying plastic polymers and calling for collaborative, open-minded research to advance this emerging field. The exchange highlights ongoing scientific debate about the reliability of current techniques for detecting nanoplastics in human tissues.

This is a response on the commentary paper by B. Wilhelmus, M. Gahleitner, and M. A. Pemberton, on our paper “Quantitation of Micro and Nanoplastics in Human Blood by Pyrolysis-Gas Chromatography–Mass Spectrometry: a follow-up study” that was published in Microplastics and Nanoplastics (2024) 4:12. We have provided answers to their questions regarding the limitations they see in the use of pyrolysis gas chromatography coupled to mass spectrometry, especially with regard to identification of polymers, quantification, sensitivity and reliability. Furthermore, a brief reflection on the state-of-the-art and the way forward to advance the quantitative analysis of micro- and nanoplastics in human materials is provided by giving a few specific recommendations. We also call for carrying out research with an open mind in multidisciplinary teams in a collaborative manner.

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