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Health impacts of micro- and nanoplastics in humans: systematic review of in vivo evidence
Summary
This review of existing research found that tiny plastic particles (called microplastics and nanoplastics) build up in different parts of the human body and may cause inflammation and organ problems. However, the studies had different methods and limitations, so scientists can't yet prove these plastics directly cause health issues. Better long-term studies are needed to understand if microplastics - which come from things like plastic bottles and food packaging - truly harm human health.
Human in vivo evidence confirms that MNPs accumulate in multiple organ systems and are associated with inflammation and functional impairment. Methodological heterogeneity and bias constrain causal inference. Prospective cohort studies with rigorous exposure assessment and confounder control are needed to advance understanding and guide policy.
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