We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Prospective Investigation of Nanoplastic Accumulation in Healthy Subjects, Autoimmune Diseases, Hematological Malignancies, Lung Cancer, and Murine Models
AI summary Read the abstract
A prospective investigation measured nanoplastic accumulation in blood samples from healthy subjects, patients with autoimmune diseases, and hematological cancer patients. The study found higher nanoplastic levels in patients with autoimmune and cancer diagnoses, raising questions about whether nanoplastic accumulation may contribute to or reflect these disease states.
Nanoplastics (NPs) and microplastics (MPs) are an emerging threat to global health. They negatively impact ecosystems and many physiological processes, causing alterations in xenobiotic metabolism, nutrient uptake, energy metabolism, or cytotoxicity. In humans, we are beginning to analyze these plastics for the mechanisms by which they enter the organism, accumulate, and diffuse as well as for their pathogenic potential. NP accumulation has been demonstrated in human tissues, such as blood or placenta, while in others it remains largely unstudied. In this work, we detected NP accumulation in bronchoalveolar lavage fluids (BALFs), cerebrospinal fluids (CSFs), lymph nodes (LNs), urine, pleural fluids (PFs), ascitic fluids (AFs), and peripheral blood (PB) by combining fluorescence and nanocytometry techniques. NP analysis was compared with two strains of mice, and the results support that inhalation is the main route of NP accumulation.
More Papers Like This
Prospective Investigation of Nanoplastic Accumulation in Healthy Subjects, Autoimmune Diseases, Hematological Malignancies, Lung Cancer, and Murine Models
AI summary Read the abstract
Researchers conducted a prospective investigation into nanoplastic accumulation in human cardiac tissue, collecting heart samples and analyzing them for nanoplastic content using sensitive analytical techniques. The study provides early evidence of nanoplastic presence in cardiac tissue and raises questions about cardiovascular health implications.
The Impact of Micro/Nanoplastics on Human Hematopoietic Function: Exposure, Deposition, Toxicity, and Mitigation Strategies
AI summary Read the abstract
Researchers reviewed how micro- and nanoplastics enter the body via diet and inhalation and accumulate in blood cells and hematopoietic organs, synthesizing animal and in vitro evidence that these particles disrupt red and white blood cell production through oxidative stress and inflammatory signaling while also exploring biodegradation and dietary mitigation strategies.
Nanoplastic-Induced Biological Effects In Vivo and In Vitro: An Overview
AI summary Read the abstract
Researchers reviewed how nanoplastics accumulate in and harm living organisms, finding that particle size, surface charge, exposure dose, and duration all influence toxicity — with smaller, charged particles penetrating cells more readily and chemical additives amplifying harm beyond the plastics themselves.
Polymer-Specific Quantification of Circulating Microplastics in Healthy and Immunocompromised Individuals
AI summary Read the abstract
Scientists found tiny plastic particles in the blood of all people they tested, but people with weakened immune systems had slightly higher levels than healthy people. The plastic pieces likely come from everyday items and medical equipment, and people with compromised immune systems may have trouble clearing them from their bodies. This research shows that microplastics are now circulating in human blood, though we still don't know what health effects this might have.
Nanoplastic occurrence, transformation and toxicity: a review
AI summary Read the abstract
Researchers reviewed the environmental fate and biological toxicity of nanoplastics, finding that these sub-micron particles weather, aggregate, and accumulate contaminants in aquatic environments, and that ingestion by microbes, algae, invertebrates, and fish disrupts growth, reproduction, and behavior.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.