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Investigating the link between microplastic exposure (benzyl butyl phthalate) and neurodegenerative diseases using high-performance computational toxicology

Toxicology Research 2024 2 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 50 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Alhamyani abdulrahman

Summary

Researchers used computational toxicology methods to investigate potential links between benzyl butyl phthalate, a plasticizer associated with microplastic exposure, and neurodegenerative diseases. The analysis revealed that this compound has the potential to interact with proteins PRKN and PDK1, which are involved in neurological function. The study suggests a possible molecular mechanism by which microplastic-associated chemicals could contribute to neurodegeneration, though further experimental validation is needed.

Overall, the computational investigation reveals that BBP has the potential to interact with PRKN and PDK1, leading to neurodegeneration.

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