Hyperspectral Retinal Imaging for Micro-and Nanoplastics Detection: A Conceptual and Methodological Framework

Hyperspectral retinal imaging for micro- and nanoplastics detection: a conceptual and methodological framework

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This conceptual paper proposed a methodological framework for using hyperspectral retinal imaging to detect micro- and nanoplastics deposited in the human eye. The authors argued that the retina's transparent optical media and vascularized layered structure make it an ideal non-invasive window for adapting spectroscopic plastic detection techniques to biomedical monitoring.

Optical innovations in microplastic analysis: a critical review of detection strategies

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Researchers reviewed the current landscape of optical detection methods for microplastics—spanning Raman and FTIR spectroscopy, SERS, FLIM, hyperspectral imaging, and AI-enhanced analysis—highlighting that while handheld and smartphone-based platforms show strong promise for field deployment, the absence of standardized protocols and interference from organic matter remain key barriers to reliable environmental monitoring.

Microplastics and Nano-plastics in Eye Health: Ocular Exposure, Toxicity, and Clinical Implications

Microplastics and Nano-plastics in Eye Health: Ocular Exposure, Toxicity, and Clinical Implications

Raman Spectroscopy Based Approaches for Microplastics Investigations

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Researchers reviewed Raman spectroscopy-based approaches — including confocal Raman microscopy, surface-enhanced Raman scattering, and automated imaging — for identifying and characterizing microplastics in environmental samples, highlighting their superior chemical specificity compared to FTIR for sub-10-μm particles. Accurate chemical identification of microplastics at the nanoscale is foundational for both environmental monitoring and toxicological research, as particle composition (polymer type and additives) strongly influences biological harm.