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Threshchronic: Concept proposal of a fuzzy bayesian tool for health support
Summary
Researchers proposed a new software tool that uses fuzzy Bayesian logic to detect threshold levels in cause-and-effect relationships for chronic disease risk factors. The tool is designed to be tested first on well-understood radioactivity data and then applied to less-studied environmental exposures like microplastics. The study aims to help establish whether safe exposure limits exist for emerging environmental contaminants that may affect human health.
A multitude of chronic diseases are not yet classified as being stochastic or deterministic. The purpose of this work was to provide an adaptative software tool which enables detection of thresholds for the cause-consequence relationships with a maximum degree of confidence given the available statistics. This tool is meant to be tested on radioactivity datasets, for which the thresholds exist and are well-known, then to be applied to other datasets on radio-activity and microplastics (environment), antibiotics (pharmacological factors), and nitrites (food industry). The main algorithm for this supporting program for health research was built as an unitary procedure for all situations, additional covariance analysis on multi-factor cases will be performed, together with a scheme which explicates the importance of transfer factors for the data recorded on various substances (e. g. water-fish-human transfer for radio- activity and microplastics). The key elements are the non-biased datasets available and the algorithms for conditional probability calculations and potential thresholds determination. One very important action to take is separating the accurate and verifiable data from the plethora of biased information from the repositories.