Article
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Tier 2
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Original research — experimental, observational, or case-control study. Direct primary evidence.
Human Health Effects
Nanoplastics
Remediation
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Elucidating the leaching effect of micro-/nano-plastics on the binding, structural, and oxidative characteristics of bovine serum albumin and its impact on cytotoxicity and oxidative stress in the human lung cancer cell line A549
Environmental Science Nano2025
4 citations
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Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Score: 58
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0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Hasan Saygın,
Aslı Baysal,
Aslı Baysal,
Hasan Saygın,
Hasan Saygın,
Hasan Saygın,
Hasan Saygın,
Aslı Baysal,
Aslı Baysal,
Hasan Saygın,
Aslı Baysal,
Hasan Saygın,
Hasan Saygın,
Hasan Saygın,
Aslı Baysal,
Hasan Saygın,
Hasan Saygın,
Hasan Saygın,
Hasan Saygın,
Hasan Saygın,
Hasan Saygın,
Hasan Saygın,
Hasan Saygın,
Hasan Saygın,
Hasan Saygın,
Aslı Baysal,
Aslı Baysal,
Aslı Baysal,
Aslı Baysal,
Aslı Baysal,
Aslı Baysal,
Aslı Baysal,
Aslı Baysal,
Aslı Baysal,
Aslı Baysal,
Aslı Baysal,
Aslı Baysal,
Aslı Baysal,
Aslı Baysal,
Ahu Soyocak,
Ahu Soyocak,
Aslı Baysal,
Hasan Saygın,
Emre Apaydin,
Ahu Soyocak,
Ahu Soyocak,
Aslı Baysal,
Aslı Baysal,
Aslı Baysal,
Mehmet Kahraman,
Emre Apaydin,
Pemra Özbek
Pemra Özbek
Emre Apaydin,
Pemra Özbek
Summary
Researchers examined how micro- and nanoplastics interact with bovine serum albumin, a key blood protein, and what happens when the altered protein contacts human lung cancer cells. They used biophysical methods and molecular docking to characterize how the plastic particles change the protein's structure and binding properties. The study found that protein-nanoplastic complexes showed increased toxicity and oxidative stress in lung cells compared to either component alone.
The binding mechanism of proteins with micro/nanoplastics are examined by biophysical/chemical indicators, and molecular docking. In addition, cytotoxicity of protein after micro/nanoplastics interaction was tested on A549 cells.