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Trends, key contributors, and emerging issues in honey and breast cancer: A bibliometric analysis from 2014 to 2024

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Andi Nilawati Usman, Fendi Fendi, Zafitri Nulandari, Dinah Inrawati Agustin

Summary

A bibliometric analysis of 2014–2024 literature on honey and breast cancer identified nine research clusters covering bioactive compounds, anticancer mechanisms, and combination therapies, revealing growing interest in honey's polyphenol content as a complementary approach to breast cancer prevention and treatment.

<ns3:p>Background Honey, a natural product with diverse bioactive compounds, has been increasingly explored for its potential anticancer properties. This study aims to comprehensively analyze the scientific literature on the relationship between honey and breast cancer. Methods A bibliometric analysis was conducted using the ScienceDirect database to identify publications from 2014 to 2024. Data on publication trends, author collaboration, and keyword analysis were extracted to gain insight into the research landscape. Keyword analysis identified nine distinct clusters, indicating diverse research directions regarding the role of honey in breast cancer treatment. Results Key journals such as the Journal of Ethnopharmacology and Food Chemistry have been at the forefront of disseminating research findings in this domain, demonstrating a strong interdisciplinary approach that bridges traditional medicine and modern scientific inquiry. The increasing interest in the anticancer properties of honey, as evidenced by the growing number of studies, underlines its potential as a promising natural agent for breast cancer prevention and treatment. Recent advances in the synthesis and theranostic paradigms of cerium oxide nanoparticles (CeONPs) have been highlighted, as well as the potential for selenium nanoconstructs. The toxicity and quality control of Perillae Fructus have also been highlighted. Conclusions This study provides a comprehensive overview of the current state of knowledge and uncovers emerging issues that require further investigation.</ns3:p>

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