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Clear Aligner Treatment: Indications, Advantages, and Adverse Effects—A Systematic Review
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This systematic review of clear aligner orthodontic treatment identified microplastics release as a potential adverse health effect, alongside decreased condyle bone volume. While clear aligners offer oral hygiene advantages over fixed braces, they remain inferior for complex tooth movements, and the microplastic exposure risk from wearing plastic aligners warrants further investigation.
Background/Objectives: Clear aligner treatment (CAT) has gained interest among clinicians as well as among patients. The aim of the present study was to systematically review the literature regarding current viewpoints on indications, contraindications, advantages, disadvantages, and adverse effects in CAT. Methods: A search was performed in the PubMed and Embase databases, yielding 18 studies eligible for inclusion. Results: Current indications for CAT are mild to moderate malocclusions. Severe malocclusions with impactions or severe craniofacial skeletal deviations are contraindications. The advantages were oral hygiene and oral health as the most common, and disadvantages of CAT have been noted by several studies, including CAT still being inferior to fixed appliance treatment (FAT) in all orthodontic movements. Adverse effects were potential health risks due to microplastics and a decrease in condyle bone volume. Conclusions: No firm conclusions can be drawn regarding indications for CAT except for mild to moderate malocclusion. Severe malocclusions with impactions or severe craniofacial skeletal deviations are considered contraindications. In more complex cases, CAT is still considered inferior to FAT, although CAT contains advantages. There are disadvantages in CAT which clinicians should consider when choosing a type of orthodontic appliance for treating specific malocclusions. Only a few adverse effects in CAT were presented by the included studies. More high-quality research is needed regarding indications and contraindications for CAT.
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Can Clear Aligners Release Microplastics That Impact the Patient’s Overall Health? A Systematic Review
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This systematic review investigates whether clear orthodontic aligners release microplastics during use in the mouth. The findings raise concerns about a previously overlooked source of direct microplastic exposure, since millions of people wear these plastic devices against their teeth and gums for months or years at a time.
Microplastic Release from Clear Aligners: a Clinical Study
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Clear teeth aligners, the plastic trays used instead of metal braces, can shed tiny plastic particles into your saliva as you wear and chew with them, according to this study. Researchers found that factors like how long you wear them each day and how you clean them affect how much plastic breaks off, meaning your daily habits could influence how much of this material ends up in your mouth. Since scientists are still learning what micro- and nanoplastics do to the body long-term, this research highlights an overlooked source of exposure worth paying attention to as more people use clear aligners for orthodontic treatment.
Assessing The Awareness and Risk of Microplastic Exposure Among Orthodontic Patients: A Questionnaire-Based Study
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A questionnaire study of 110 orthodontic patients, including 52 clear aligner users, found low awareness that clear aligners may release microplastics. Diet was identified as the biggest source of microplastic exposure, and most participants believed plastic exposure could harm health, though the study did not test actual exposure levels.
Orthodontic Clear Aligners as a Potential Source of Microplastic Exposure: Implications for Human Health and Environmental Sustainability
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If you're using clear plastic aligners to straighten your teeth (like Invisalign), this review of existing research suggests that everyday wear and tear from chewing and saliva may cause them to shed tiny plastic particles into your mouth. Scientists don't yet know how much this affects your health, but it adds to growing concerns about microplastics — tiny plastic fragments already found throughout the human body — while also raising questions about the environmental waste from millions of discarded aligners. More research is needed before we know if this is something to actually worry about.
Aligners do shed microplastics: Evidence is clear, clinical risk is not
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Clear aligners (the plastic trays used instead of metal braces) do release tiny plastic particles called microplastics as you wear them, according to this review of existing research. However, scientists still don't know whether these small amounts actually cause health problems, so the takeaway isn't "stop using aligners" but rather "more research is needed" to understand any real-world risk.
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