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Effects of microplastic concentration, composition, and size on Escherichia coli biofilm-associated antimicrobial resistance

Applied and Environmental Microbiology 2025 31 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count.
Neila Gross, Johnathan Muhvich, Carly Ching, Bridget Gomez, Erika Horváth, Yanina Nahum, Yanina Nahum, Muhammad H. Zaman

Summary

This study examined how different types of microplastics affect the development of antibiotic-resistant bacteria through biofilm formation. The researchers found that the concentration, composition, and size of microplastic particles all influence how effectively bacteria like E. coli develop drug resistance. These findings are important because they help explain how widespread plastic pollution may be contributing to the growing global crisis of antibiotic resistance.

Antimicrobial resistance (AMR) is one of the world's most pressing global health crises. With the pipeline of antibiotics running dry, it is imperative that mitigation strategies understand the mechanisms that drive the genesis of AMR. One emerging dimension of AMR is the environment. This study highlights the relationship between a widespread environmental pollutant, microplastics (MPs), and the rise of drug-resistant bacteria. While it is known that MPs facilitate resistance through several modes (biofilm formation, plastic adsorption rates, etc.), this study fills the knowledge gap on how different types of MPs are contributing to AMR.

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