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Microplastics: Health Hazards and the Way Forwrad

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This review summarizes existing research on microplastics, tiny plastic particles under 5 mm found throughout ecosystems and the food chain. It describes how microplastics may enter and move through the human body, potentially causing tissue damage, immune reactions, oxidative stress and inflammation after prolonged exposure. The authors note that measuring exact health risks remains difficult due to differences between plastic types.

Body Systems

Microplastics (MPs) are tiny pieces of plastics, less than 5 mm in size. They cause a type of pollution that has become a public health concern worldwide.. Current studies have increasingly focused on understanding the possible health hazards of MPs exposure on the human body. This review seeks to highlight the exposure pathways, pathophysiology and toxicity of MPs as well as proffer possible solutions.. Previous works and research findings on this subject were accessed through Google Search, PubMed, and Wikipedia websites. In addition, standard textbooks on Pharmacology were consulted. Sources of MP pollution include plastic degradation products, textile fibres, tire degradation products, etc. The MPs have been detected across different ecosystems and have been found to infiltrate the food chain, raising concerns about their potential impacts on human health. On entering the human body MPs move through various tissues and organs and cause health hazards by localized toxicity and by triggering immune response. DNA damage, oxidative stress and inflammatory reaction can occur after prolonged exposure to MPS. At present, determination of reference values of plasma concentration of MPs is difficult because different nanoplastics have different toxicities making standardization difficult and most harmful effects of microplastics occur after prolonged exposure. Measures of limiting exposure to MPs pollution including avoidance of serving or storing hot dishes and drinks in plastic containers, avoidance of perfumes and roll-ons that contain polymers, among others were highlighted.

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