We can't find the internet
Attempting to reconnect
Something went wrong!
Hang in there while we get back on track
Investigation of the Effects of Interactions Between Deltamethrin and Acrylic Paint Particles on Embryonic Development in Xenopus laevis
AI summary Read the abstract
Frog embryos were exposed to the pesticide deltamethrin, acrylic paint particles, or both together. Deltamethrin alone caused death and developmental problems, while paint alone had little effect. Combined exposure changed deltamethrin's effects, in some cases increasing survival, depending on the dose and paint type.
The co-occurrence of pesticides and paint-related contaminants in aquatic ecosystems may result in interactions that modify their individual toxic effects; however, the developmental consequences of their combined exposure remain insufficiently understood. This study investigated the individual and combined effects of the widely used pyrethroid insecticide deltamethrin (DM) and two acrylic paints, which have a high potential for microplastic formation, on Xenopus laevis embryonic development, with particular emphasis on their interaction during co-exposure. Embryos at Nieuwkoop and Faber stages 8–11 were exposed for 96 h to two nominal DM concentrations (13.6 and 6.8 µg/L), to acrylic paint (100 mg/L), and to their respective combinations. Mortality, malformation rate, phenotypes, body length, and heart rate were evaluated. DM produced marked developmental toxicity, including complete mortality at the higher concentration, and substantial malformations, reduced body length, and altered heart rate at the lower concentration. Exposure to acrylic paints alone produced limitedeffects on the assessed endpoints. Under co-exposure conditions, the effects of acrylic paints varied according to the DM concentration and the developmental endpoint. At the higher DM concentration, both paints markedly increased embryo survival, whereas this effect was less pronounced at the lower concentration. Across the remaining endpoints, co-exposure modified DM-associated effects in both directions, depending on the paint and the endpoint evaluated. These findings suggest that co-exposure to acrylic paint may modify DM-related developmental toxicity, highlighting the importance of considering contaminant interactions in aquatic environmental and public health risk assessments.
More Papers Like This
The single and combined effects of deltamethrin and polyethylene microplastics on the development and biochemical responses of Xenopus laevis in early life stages
AI summary Read the abstract
Researchers tested the single and combined effects of the pesticide deltamethrin and polyethylene microplastics on the African clawed frog during early development. While microplastics alone did not cause visible malformations or mortality, they altered biochemical enzyme activities and, when combined with the pesticide, produced complex interaction patterns including both additive and antagonistic effects. The study suggests that microplastic co-exposure can modify how aquatic organisms respond to pesticide toxicity.
Developmental toxicity of co-exposure of heavy metal and polystyrene microplastics in Xenopus laevis embryo
AI summary Read the abstract
Researchers exposed Xenopus laevis frog embryos simultaneously to cadmium, copper, lead, and polystyrene microbeads, finding that co-exposure produced more complex effects than any single contaminant and that interactions included antagonistic as well as additive outcomes.
Microplastics and TiO2 nanoparticles mixture as an emerging threat to amphibians: A case study on bullfrog embryos
AI summary Read the abstract
Scientists studied the combined effects of polyethylene microplastics and titanium dioxide nanoparticles on bullfrog embryo development. While the microplastics alone did not significantly harm the embryos because they stuck to the outer protective layer, the nanoparticles reduced survival and hatching rates. This study shows that different types of tiny particles can interact in complex ways in the environment, and that amphibian embryos may be more vulnerable to nanoparticles than to microplastics during early development.
Combined neurotoxicity of aged microplastics and thiamethoxam in the early developmental stages of zebrafish (Danio rerio)
AI summary Read the abstract
This study found that aged (weathered) microplastics combined with the insecticide thiamethoxam caused worse neurological damage to zebrafish larvae than either pollutant alone. The combined exposure reduced heart rate and movement, disrupted antioxidant defenses, and altered neurotransmitter levels in ways that were synergistic rather than simply additive. This is relevant to human health because both microplastics and pesticides are common in the environment, and their combined effects may pose greater risks than either one individually.
Interaction of microplastics and pesticides in the environment
AI summary Read the abstract
This Croatian thesis reviews the interactions between microplastics and pesticides in aquatic environments, examining how microplastics can adsorb and transport pesticide contaminants. The author discusses combined toxicity effects and the environmental implications of this co-contamination.
Research digests by email
When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.