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Data package for: Micro- and nanoplastics in human reproduction - from analytical validity to actionable mechanistic and clinical roadmaps
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This is a supplementary data file, not a new study. It contains 118 reference papers and a quality-check scorecard, including 15 core studies on detecting microplastics, that were used to support a review article on microplastics and nanoplastics in human reproduction.
Corpus of 118 Crossref-verified references and the full-text QA/QC scorecard (15 core detection studies, 8 dimensions) supporting the narrative review submitted to Reproductive Biology and Endocrinology.
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Data package for: Micro- and nanoplastics in human reproduction - from analytical validity to actionable mechanistic and clinical roadmaps
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Scientists reviewed existing research on tiny plastic particles (microplastics and nanoplastics) and their possible effects on fertility and reproduction, checking how reliable the detection methods really are. This paper itself is more of a background dataset and quality check than a new discovery. It matters because it lays the groundwork for future studies to better understand whether these plastics genuinely affect reproductive health.
Plastic pollution in human reproduction: should we worry?
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Researchers reviewed evidence that micro- and nanoplastics can cross the placenta, enter amniotic fluid, and accumulate in reproductive tissues in both men and women. Animal and cell studies suggest these particles may reduce egg and sperm quality and harm fetal development, though most experiments use higher doses than people realistically encounter.
Reproductive toxicity of micro‐ and nanoplastics: Insights from experimental and human studies
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This review examined 40 studies on how micro- and nanoplastics may affect human reproduction, finding that these particles have been detected in breast milk, placenta, ovaries, testes, and semen. Animal studies have linked plastic particle exposure to reduced sperm quality, disrupted egg development, smaller litter sizes, and possible effects passed to future generations. The evidence suggests that microplastic exposure may be a contributing factor worth investigating as global fertility rates continue to decline.
Plastic Particles and Female Fertility: Pathways, Toxicity, and Analytical Challenges
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This review examines the pathways, toxicity mechanisms, and analytical challenges associated with microplastic and nanoplastic impacts on female fertility. Evidence from animal studies indicates that these particles can accumulate in ovaries and placental tissue, inducing oxidative stress, inflammation, and granulosa cell death that diminishes ovarian reserve. The study notes that microplastics have been confirmed in human placentas and umbilical cord blood, and may disrupt the hormonal axis governing reproduction.
Plastics in human reproductive tissues: A systematic review of detection, characterization, and effects on fertility.
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This review summarizes 41 studies on tiny plastic particles found in human reproductive tissues, including semen, testis, follicular fluid, and placenta. These particles were linked to cell stress, metabolic changes, and in some studies, poor sperm motility, though effects on ovarian markers and fertility outcomes were inconsistent across studies.
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When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.