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Microplastics and Nanoplastics in Human Blood: What the Latest Research Shows

Zenodo (CERN European Organization for Nuclear Research) 2026
James Wooddell

Summary

Tiny plastic particles called microplastics and nanoplastics have been found circulating in human blood, and this review pulls together what scientists have learned so far about where they come from and how they might affect us. Early studies suggest possible links to heart problems, blood clotting issues, and cell damage, though researchers stress it's not yet proven that plastics *cause* these problems. The review also looks at whether things like blood donation might help clear plastics from the body, but notes that more research is needed before we know how worried to be.

Body Systems
Models

This article reviews recent evidence that microplastics and nanoplastics circulate in human blood. It summarizes landmark detection studies from 2022–2026, including pyrolysis-GC/MS, µFTIR, Raman, and flow-cytometry findings, and discusses associations with cardiovascular disease, plaque vulnerability, coagulation, and cellular injury. It also examines whether therapeutic plasma exchange or blood donation can reduce circulating particle burden, notes methodological limits and contamination risks, and frames remaining questions of causation and mitigation.

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