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Morphological, physiological, and molecular responses of Perilla frutescens to copper stress alleviated by PVC microplastics

Plant Physiology and Biochemistry 2025 3 citations ? Citation count from OpenAlex, updated daily. May differ slightly from the publisher's own count. Score: 58 ? 0–100 AI score estimating relevance to the microplastics field. Papers below 30 are filtered from public browse.
Zhizhong Zhang Fenghang Sun, Fenghang Sun, Xinyue Yang, Fenghang Sun, Fenghang Sun, Fenghang Sun, Fenghang Sun, Xinyue Yang, Lixian Xu, Xinyue Yang, Jingyun Hu, Lixian Xu, Jinghua Wu, Jingyun Hu, Lixian Xu, Lixian Xu, Gefu Wang‐Pruski, Gefu Wang‐Pruski, Jinghua Wu, Jinghua Wu, Gefu Wang‐Pruski, Jinghua Wu, Zhizhong Zhang Zhizhong Zhang Gefu Wang‐Pruski, Zhizhong Zhang

Summary

Researchers discovered that low concentrations of PVC microplastics can actually reduce the harmful effects of copper on perilla plants, an important crop. The microplastics appeared to help by improving cell membrane function, suppressing stress hormones, and adjusting fat metabolism pathways. While this does not mean microplastics are beneficial overall, the study reveals surprisingly complex interactions between plastic pollution and heavy metals in agricultural environments.

Polymers

Microplastics (MPs) and copper (Cu) are common co-pollutants in agricultural environments, yet their combined effects on plants remain poorly understood. This study investigated the individual and interactive impacts of Cu and polyvinyl chloride (PVC)-MPs on Perilla frutescens, a heavy metal hyperaccumulator and economically important crop, using hydroponic experiments. Low Cu concentrations (<2 mg L) promoted growth, whereas higher levels (>2 mg L) induced leaf chlorosis, curling, and root decay. PVC-MPs alone exhibited phytotoxicity only at high concentrations (>1000 mg L). In combined treatments, 10-100 mg L PVC-MPs alleviated Cu-induced chlorosis and increased leaf area, though higher MP concentrations suppressed root growth. Physiologically, Cu stress impaired photosynthesis, enhanced antioxidant enzyme activity, and increased osmoregulatory substance content. PVC-MPs counteracted these effects by improving photosynthetic efficiency, enhancing peroxidase activity, and reducing osmotic stress markers. Transcriptomic analysis revealed that PVC-MPs upregulated endocytosis-related genes while downregulating jasmonic acid (JA) biosynthesis and lipid metabolism pathways. ABC transporter genes were differentially expressed, functionally linked to these processes. We demonstrate for the first time that PVC-MPs mitigate Cu stress via three synergistic mechanisms: enhanced membrane trafficking (endocytosis activation), suppression of stress-signaling phytohormones (JA), and lipid metabolism reprogramming. These findings redefine MPs' dual role as both pollutants and unexpected alleviators of metal toxicity. While these findings reveal MPs' unexpected capacity to alleviate metal stress, their persistent environmental accumulation necessitates comprehensive risk-benefit analysis and long-term ecological monitoring-highlighting the imperative for science-based evaluation rather than promoting field applications of MPs as stress mitigants.

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