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Development of a low-cost Raman spectroscopy platform for high-throughput analysis

2025

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Researchers developed a low-cost, high-throughput Raman spectroscopy platform combining a CNC stage, USB microscope, and Raman probe for automated microplastic analysis, validating the system by scanning polypropylene microplastics scattered on glass filters across defined sample areas.

Polymers

This study describes the development of a low-cost, high-throughput Raman spectroscopy platform for rapid sample analysis. The system consists of 3 main components: a CNC, a USB microscope and a Raman probe, providing a cheaper alternative to commercial systems. The platform combines automated particle coordinates identification with the microscope, followed by a Raman analysis to characterize the sample across a defined area. To validate the proposed system, polypropylene (PP) microplastics were scattered on a glass filter and subjected to the scan. The system scanned an area of 519.84 mm2 in under 1 hour, detected 481 particles through the microscope and 170 of the spectra acquired with Raman, were identified as PP, demonstrating its capability as an efficient and cost-effective solution. Despite this, the proposed platform is versatile and can be used for different applications, namely when evaluating Raman sensitive coatings through a Raman map, for example on optical fibers.

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