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From Aquatic Pollution to Drinking-Water Exposure: Analytical Challenges in Detecting Nanoplastics in Drinking Water—A PRISMA-Guided Review

Original title: From Aquatic Pollution to Drinking-Water Exposure: Analytical Challenges in Detecting Nanoplastics in Drinking Water—A PRISMA-Guided Review

Preprints.org 2026
José Roberto Vega-Baudrit, Mary Lopretti, Felipe Orozco

Summary

Scientists still can't reliably measure the tiniest plastic particles (called nanoplastics) in our drinking water, mainly because current lab tools aren't precise enough to detect them accurately or tell us exactly what they're made of. This review of 22 existing studies found that the problem isn't just pollution levels—it's that our detection methods themselves need major improvement before we can even know how much nanoplastic exposure we're really getting from tap water, let alone what it means for our health.

Study Type Environmental

Nanoplastics (NPs) in drinking water should be interpreted as the downstream analytical endpoint of a broader continuum of aquatic plastic pollution rather than as an isolated problem. Their detection remains analytically immature because environmentally relevant concentrations are low, particle chemistries are heterogeneous, natural colloids and treatment residuals interfere with measurement, and no single method can simultaneously resolve size, morphology, polymer identity, and mass concentration. Unlike occurrence-centered reviews, this PRISMA-guided review treats drinking-water nanoplastics as a metrological and molecular-identification problem in which preprocessing, particle-level confirmation, polymer-specific quantification, and uncertainty reporting must be integrated. A formal search was closed on 11 April 2026 using prespecified query families across publicly accessible scholarly records and backward citation chaining; 33 unique records were screened, 25 full texts were assessed, and 22 studies were included in the qualitative synthesis. Current evidence indicates that conventional FTIR and routine Raman workflows are inadequate for true nanoscale analysis, whereas advanced Raman-based approaches, AFM-IR, optical photothermal infrared spectroscopy, surface-enhanced Raman spectroscopy, and pyrolysis-gas chromatography-mass spectrometry offer complementary strengths but still have major limitations in throughput, particle-level information, or quantification. The main conclusion is that current uncertainty reflects unresolved analytical chemistry and metrological constraints as much as environmental variability. Regulatory progress will depend on orthogonal workflows, contamination-controlled preprocessing, validated reference materials, LOD/LOQ reporting, and interlaboratory harmonization.

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