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Multiple-biomarker approach in the assessment of bisphenol A effect on the grooved carpet clam Ruditapes decussatus (Linnaeus, 1758)
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Researchers exposed grooved carpet clams to bisphenol A (BPA) in water and found it caused oxidative stress, neurotoxicity, genotoxicity, and damage to the digestive gland, demonstrating that multi-biomarker approaches can effectively reveal the wide-ranging harm that plastic-associated chemicals inflict on marine bivalves.
The multi-biomarker approach used in the current study proved to be a useful tool for assessing the impact of diphenylmethane compounds, such as BPA. Water-borne BPA causes oxidative stress, neurotoxicity, genotoxicity, and deleterious effects on the clam digestive gland; all of these could deteriorate clam performance and health, causing tissue dysfunction.
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Ecotoxicological effects and bioaccumulation of BPA analogues and their mixture in the clam Ruditapes philippinarum
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Researchers exposed clams to three common bisphenol A substitutes (BPAF, BPF, and BPS) at environmentally relevant concentrations to evaluate whether these replacement chemicals are truly safer. The study found that all three BPA analogues caused oxidative stress, cellular damage, and neurotoxic effects in clam tissues, suggesting that these widely used substitutes may pose similar ecological risks as the compound they were designed to replace.
Assessing the Effects of a Diet of BPA Analogues-Contaminated Microalgae in the Clam Ruditapes philippinarum
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Researchers fed the clam Ruditapes philippinarum a diet of microalgae that had bioaccumulated bisphenol A analogues, finding measurable transfer of BPA substitutes through the food chain into bivalve tissue, raising concerns about trophic exposure to plastic-associated endocrine disruptors in marine food webs.
Assessing the Effects of a Diet of BPA Analogue-Exposed Microalgae in the Clam Ruditapes philippinarum
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This research examines whether BPA analogues — chemicals used as replacements for bisphenol A — can transfer through the food chain when fish consume microalgae that have been exposed to these compounds. The study found measurable uptake of BPA analogues in fish tissues, suggesting trophic transfer is a meaningful exposure pathway. These results raise concerns about the safety of BPA substitutes and the broader ecological impacts of plastic-associated endocrine-disrupting chemicals.
Muti-Biomarker Approach and IBR Index to Evaluate the Oxidative Stress of Nanoplastic on the Clams, Meretrix meretrix and Sinonovacula constricta
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Researchers exposed two clam species to polystyrene nanoplastics and measured antioxidant enzyme responses across multiple tissues, finding that oxidative stress patterns varied by species, organ, dose, and time, with gills showing the highest sensitivity and damage levels returning to baseline after a recovery period.
Immunotoxicity and neurotoxicity of bisphenol A and microplastics alone or in combination to a bivalve species, Tegillarca granosa
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Researchers investigated the immunotoxicity and neurotoxicity of bisphenol A and microplastics, both alone and in combination, on the blood clam Tegillarca granosa. The study found that co-exposure to both pollutants produced significant impacts on immune and neural biomarkers, suggesting that the combined presence of microplastics and chemical contaminants may pose greater risks to marine invertebrates.
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When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.