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Studying the Interaction of Nano- & Microplastics with Enterovirus and Their Cytotoxicity on Human Lung Cell Line
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This master's thesis studied the interaction between nano- and microplastics and enteroviruses, examining whether plastic particles can act as carriers for viral pathogens and testing cytotoxic effects on a human lung cell line.
Master's
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Toxicological effects of different particle sizes and types of nano-plastics (NPs) on human lung cells: implications for the health risk of airborne microplastic pollution
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Researchers exposed human A549 alveolar cells to polystyrene and polymethylmethacrylate nanoplastics of 30 and 50 nm and found that smaller size and higher concentration produced stronger cytotoxicity, oxidative stress, inflammation, and apoptosis—with PS nanoparticles more toxic than PMMA—providing in vitro evidence of respiratory health risks from inhaled airborne nanoplastics.
Microplastics as Vectors for Viral Transmission: Mechanisms, Influencing Factors, and Ecological-Health Risks
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Tiny plastic particles floating in the environment can stick to viruses and help them survive longer and spread more easily, which could increase the risk of getting sick. This review article summarizes what scientists have learned about how plastics and viruses interact, and why it matters, because many of us are now exposed to both microplastics and viruses at the same time, which could be worse for our immune systems than facing either threat alone. Understanding this problem better will help researchers figure out how to protect public health as plastic pollution continues to grow worldwide.
The potential role of micro- and nanoplastics in the spread of viruses
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This review examines how micro- and nanoplastics may act as vehicles that amplify the spread and infectivity of pathogenic viruses in humans and animals, explaining that the plastisphere (the microbial community living on plastic surfaces) can preserve viruses and that plastics weaken the body's natural barrier tissues. The authors warn that plastic particles carrying viruses could increase infection risk and potentially even help viruses develop new variants, calling for urgent interdisciplinary research.
Enteric virus infection was boosted by the accumulation of micro- and nano-particles in host cells
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Researchers discovered that polystyrene micro- and nanoplastics can boost viral infection by promoting the release of virus-carrying extracellular vesicles from host cells. In experiments with murine norovirus, pre-exposure to the plastic particles enhanced viral spread while simultaneously suppressing key immune responses. The study identifies a previously unrecognized mechanism by which environmental plastic pollution could increase vulnerability to enteric virus infections.
Survival of human enteric and respiratory viruses on plastics in soil, freshwater, and marine environments
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Researchers investigated the survival of human enteric and respiratory viruses on plastic surfaces in soil, freshwater, and marine environments. The study found that plastics and microplastics can harbor pathogenic viruses in addition to bacteria, suggesting that the so-called plastisphere may serve as a previously underappreciated pathway for the transmission of human pathogens in the environment.
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When a large batch of papers lands in the Atlas, we read through it and send a short write-up of what stood out.